Sarissa Biomedical Translating biomedical research into everyday care

Sarissa Biomedical

Translating biomedical research into everyday care

Latest Articles

The Catchment Is Part of the Test: Measuring Diagnostic Reach in UK Primary Care
Diagnostics and Primary Care

The Catchment Is Part of the Test: Measuring Diagnostic Reach in UK Primary Care

Diagnostic quality is usually discussed in terms of assay performance, turnaround time and clinical interpretation. This article argues that reachable collection capacity belongs in the same conversation, and sets out a practical way to map catchments, identify diagnostic deserts and commission collection services around the people least able to travel.

Before the Reorder: A Clinical Framework for Repeat Diagnostics in UK Care
Clinical Testing Literacy

Before the Reorder: A Clinical Framework for Repeat Diagnostics in UK Care

A repeat diagnostic request is often treated as a neutral reset, but it commits time, samples and patient attention to a specific hypothesis. This article sets out a practical framework for deciding when repetition confirms a result, when it conceals a pathway problem, and when it should prompt a different clinical conversation altogether.

Diagnostics and Primary Care

The Loop That Stays in English: Language Access in UK Diagnostic Follow-Up

UK diagnostic services increasingly translate consent forms and kit instructions, yet result letters, portal messages, reference ranges and follow-up calls often revert to English. This article maps where language access breaks down after the sample is taken and sets out a practical checklist for multilingual result delivery, ownership and audit.

The Same Kit, a Different Test: Change Control for Connected Diagnostics in UK Care
Diagnostics and Primary Care

The Same Kit, a Different Test: Change Control for Connected Diagnostics in UK Care

Connected home tests now change through firmware and algorithm updates long after launch, so a device validated in one version may behave differently months later. This article sets out the minimum change-control record that UK clinicians, manufacturers and ICS commissioners need so that a validated diagnostic remains clinically comparable in everyday care.

The Missing Paragraph: Why a Home Test Result Needs a Record, Not a Screenshot
Diagnostics and Primary Care

The Missing Paragraph: Why a Home Test Result Needs a Record, Not a Screenshot

Home diagnostics can generate clinically useful information, but that information often stops at a PDF, an app inbox or a patient's camera roll. This article sets out the practical conditions — identity, consent, coding, provenance and workflow — that must be met before a home result can be safely acted on in the NHS record.

The Ledger Beside the Result: Counting the People a Diagnostic Test Never Reached
Public Health Surveillance

The Ledger Beside the Result: Counting the People a Diagnostic Test Never Reached

Diagnostic evaluations often report sensitivity and specificity as though the tested group were the whole population. This article argues for a population ledger beside the performance score, so commissioners, clinicians and health-tech companies can see who was never invited, never tested or never followed up.

The Second Pair of Hands: Consent, Custody and Communication in Proxy Home Testing
Diagnostics and Primary Care

The Second Pair of Hands: Consent, Custody and Communication in Proxy Home Testing

Home diagnostics are usually designed around a single capable user, yet many kits are completed by carers, relatives or care staff on behalf of someone else. This article sets out what UK providers and clinicians need to resolve on consent, sample custody, safeguarding and result communication when the person administering the test is not the person the result is about.

The Unopened Envelope: Auditing the Home Test Kits That Never Get Used
Diagnostics and Primary Care

The Unopened Envelope: Auditing the Home Test Kits That Never Get Used

Home diagnostic kits are ordered, delivered and then sometimes left unopened. This article examines why non-use is an invisible gap in UK diagnostic care, sets out a practical audit framework for providers, and argues that an unused kit should be treated as clinical signal rather than silent failure.

Measuring the Return Journey: A Round-Trip Standard for Community Diagnostics
Diagnostics and Primary Care

Measuring the Return Journey: A Round-Trip Standard for Community Diagnostics

Mobile units and community phlebotomy are often judged by how far they travel from a hospital. A more useful test of access is the whole round trip: whether a test is offered, reached, transported within its window and acted on. This article sets out a practical standard for commissioners and practice teams.

The Supported Lifetime: Making Diagnostic Device End-of-Life a Clinical Responsibility
Diagnostics and Primary Care

The Supported Lifetime: Making Diagnostic Device End-of-Life a Clinical Responsibility

Connected diagnostic devices are now part of routine UK care, yet their retirement is often treated as an IT or procurement afterthought. This article argues that end-of-life planning should be a clinical responsibility, with contracts, registers and migration pathways that protect patients rather than abandon them.

What the Kit Wasn't Looking For: Incidental Results in UK Home Diagnostics
Clinical Testing Literacy

What the Kit Wasn't Looking For: Incidental Results in UK Home Diagnostics

Home tests are designed around a single question, but they can return answers to questions nobody asked. This article sets out the consent, disclosure and follow-up obligations that incidental findings create for UK consumer kits and NHS-adjacent diagnostic services in 2026.

The Journey Is the Assay: Cold-Chain Accountability in UK Home Diagnostics
Diagnostics and Primary Care

The Journey Is the Assay: Cold-Chain Accountability in UK Home Diagnostics

Home-testing services are often judged on laboratory performance, yet the specimen's real test begins at the doorstep. This article examines how courier handoffs and winter temperatures can alter results, and what providers, commissioners and clinicians should verify before recommending a kit.

Reference Ranges Are Not Reassurance: Designing Lab Results for the NHS App
Clinical Testing Literacy

Reference Ranges Are Not Reassurance: Designing Lab Results for the NHS App

Direct access to laboratory results is now part of everyday UK care, but a PDF or portal entry rarely arrives with the context needed to interpret it. This article sets out a practical framework for clinicians and health-tech designers to present ranges, uncertainty and next steps without turning transparency into self-diagnosis.

The Scan You Paid For: Who Owns the Follow-Up?
Diagnostics and Primary Care

The Scan You Paid For: Who Owns the Follow-Up?

Private full-body MRI packages are producing incidental findings that arrive in general practice without a clear owner. This article sets out a practical handover and triage framework for UK clinicians, and the consent points private providers should make clear before anyone pays for imaging.

When Home and Clinic Readings Diverge: A Practical Reconciliation Framework for UK Clinicians
Clinical Testing Literacy

When Home and Clinic Readings Diverge: A Practical Reconciliation Framework for UK Clinicians

Home blood-pressure monitors, glucose meters and pulse oximeters increasingly produce numbers that disagree with clinic measurements. This article sets out a plain-English approach to validation, calibration drift, technique and traceability, and offers a clinician-facing framework for separating noise from device error and genuine clinical signal.

The Cheapest Tube in the Room: Rethinking Diagnostic Value Beyond Unit Price
Diagnostics and Primary Care

The Cheapest Tube in the Room: Rethinking Diagnostic Value Beyond Unit Price

A low unit price can conceal a costly diagnostic pathway. This analysis sets out a practical total-pathway cost model for UK commissioners and clinical teams, showing why the better buy is often the test that produces a timely, actionable result rather than the one with the smallest invoice.

The Unfinished Result: Making Diagnostic Follow-Up Accountable in UK Care
Diagnostics and Primary Care

The Unfinished Result: Making Diagnostic Follow-Up Accountable in UK Care

A diagnostic result is an intermediate event, not an endpoint. This article examines the last mile of testing in UK care: how abnormal findings are communicated, owned and safety-netted across primary and secondary care, and why digital portals and AI triage should be judged by closed-loop follow-up rather than result delivery alone.

Between the Needle and the Report: A Practical Map of the UK Blood Sample Pathway
Clinical Testing Literacy

Between the Needle and the Report: A Practical Map of the UK Blood Sample Pathway

A routine blood test is often described as a single event, yet it is a sequence of handoffs, checks and queues. This article maps the journey from GP surgery to laboratory report in 2026, showing where delays, rejections and interpretation gaps can emerge and what clinicians and patients can reasonably ask.

After the Launch: Post-Market Surveillance as Everyday Diagnostic Care
Diagnostics and Primary Care

After the Launch: Post-Market Surveillance as Everyday Diagnostic Care

A diagnostic or health-software product does not stop changing once it reaches routine care. This article examines how post-market problems surface in UK practice, what MHRA and NHS reporting routes require, and why a transparent correction can strengthen rather than undermine clinical trust.

The Address on the Sample Tube: Local Validation for Home Diagnostic Kits
Clinical Testing Literacy

The Address on the Sample Tube: Local Validation for Home Diagnostic Kits

A laboratory assay can be analytically sound and still make a poor home-testing pathway. This article sets out why local validation matters for at-home blood, saliva and urine kits in the UK, and offers a plain-English checklist for clinicians, commissioners and consumers.

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