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  • Frenguelli BG, Wall MJ (2015) Combined electrophysiological and biosensor approaches to study purinergic regulation of epileptiform activity in cortical tissue. J Neurosci Methods.
  • Babich V, Vadnagara K, Di Sole F (2015) Dual Effect of Adenosine A1 Receptor Activation on Renal O2 Consumption. J Cell Physiol 230:3093-3104.
  • Wall MJ, Richardson MJ (2015) Localized adenosine signaling provides fine-tuned negative feedback over a wide dynamic range of neocortical network activities. J Neurophysiol 113:871-882.
  • Bjerring PN, Dale N, Larsen FS (2015) Acute hyperammonemia and systemic inflammation is associated with increased extracellular brain adenosine in rats: a biosensor study. Neurochem Res 40:258-264.
  • Lindquist BE, Shuttleworth CW (2014) Spreading depolarization-induced adenosine accumulation reflects metabolic status in vitro and in vivo. J Cereb Blood Flow Metab 34:1779-1790.
  • zur Nedden S, Doney AS, Frenguelli BG (2014) Modulation of intracellular ATP determines adenosine release and functional outcome in response to metabolic stress in rat hippocampal slices and cerebellar granule cells. J Neurochem 128:111-124.
  • Diogenes MJ, Neves-Tome R, Fucile S, Martinello K, Scianni M, Theofilas P, Lopatar J, Ribeiro JA, Maggi L, Frenguelli BG, Limatola C, Boison D, Sebastiao AM (2014) Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase. Cerebral cortex 24:67-80.
  • Van Gompel JJ, Bower MR, Worrell GA, Stead M, Chang SY, Goerss SJ, Kim I, Bennet KE, Meyer FB, Marsh WR, Blaha CD, Lee KH (2014) Increased cortical extracellular adenosine correlates with seizure termination. Epilepsia 55:233-244.
  • Stone AJ, Evanson KW, Kluess HA (2014) ATP metabolism in skeletal muscle arterioles. Physiological Reports 2:e00207.
  • Sims RE, Dale N (2014) Activity-dependent adenosine release may be linked to activation of Na+-K+ ATPase: an in vitro rat study. PLoS ONE 9: e87481.
  • Carter RE, Seidel JL, Lindquist BE, Sheline CT, Shuttleworth CW (2013) Intracellular Zn2+ accumulation enhances suppression of synaptic activity following spreading depolarization. J Neurochem 125:673-684.
  • Wall MJ, Dale N (2013) Neuronal transporter and astrocytic ATP exocytosis underlie activity-dependent adenosine release in the hippocampus. J Physiol 591:3853-3871.
  • Ena SL, De Backer JF, Schiffmannn SN, de Kerchove d'Exaerde A (2013) FACS array profiling identifies ecto-5′ nucleotidase as a striatopallidal neuron-specific gene involved in striatal-dependent learning. J Neurosci 33: 8794-8809.
  • Sims RE, Wu HH, Dale N (2013) Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of rodents: an in vitro study. PLoS One 8:e53814.
  • Lindquist BE, Shuttleworth CW (2012) Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices. Neuroscience 223:365-376.
  • Heinrich A, Ando R, Turi G, Rozsa B, Sperlagh B (2012) K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharm 167:1003-1020.
  • Schmitt LI, Sims RE, Dale N, Haydon PG (2012) Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine. J Neurosci 32:4417-4425.
  • Klyuch BP, Dale N, Wall MJ (2012) Deletion of ecto-5'-nucleotidase (CD73) reveals direct action potential-dependent adenosine release. J Neurosci 32:3842-3847.
  • Yang, G.K., Squires, P.E., Tian F., Kieffer, T.J., Kwok, Y. N. and Dale, N. (2012) Glucose decreases extracellular adenosine levels in isolated mouse and rat pancreatic islets. Islets doi: 10.4161/isl.4.1.19037.
  • Wang W, Liu X, Schneider B, Zverina EA, Rus K, Wijeyesakere SJ, Fierke CA, Richardson RJ, Philbert MA (2012) Mixed Inhibition of Adenosine Deaminase Activity by 1,3-Dinitrobenzene: A Model for Understanding Cell-Selective Neurotoxicity in Chemically-Induced Energy Deprivation Syndromes in Brain. Toxicol Sci 125:509-521.
  • Otsuguro K, Wada M, Ito S (2011) Differential contributions of adenosine to hypoxia-evoked depressions of three neuronal pathways in isolated spinal cord of neonatal rats. Br J Pharmacol 164:132-144.
  • Shen HY, Lusardi TA, Williams-Karnesky RL, Lan JQ, Poulsen DJ, Boison D (2011) Adenosine kinase determines the degree of brain injury after ischemic stroke in mice. J Cereb Blood Flow Metab 31:1648-1659.
  • Klyuch BP, Dale N, Wall MJ (2011) Receptor-mediated modulation of activity-dependent adenosine release in rat cerebellum. Neuropharmacology doi:10.1016/j.neuropharm.2011.09.007
  • zur Nedden S, Hawley S, Pentland N, Hardie DG, Doney AS, Frenguelli BG (2011) Intracellular ATP influences synaptic plasticity in area CA1 of rat hippocampus via metabolism to adenosine and activity-dependent activation of adenosine A1 receptors. J Neurosci 31:6221-6234.
  • Klyuch B, Richardson MJE, Dale N, Wall MJ (2011) The dynamics of single spike-evoked adenosine release in the cerebellum. J Physiol 589:283-295.
  • Lopatar J, Dale N, Frenguelli BG (2011) Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: evidence from purine biosensors and P2 receptor agonists and antagon sits. Neuropharmacology 61: 25-34.
  • Wall M, Eason R, Dale N (2010) Biosensor measurement of purine release from cerebellar cultures and slices. Purin Signalling 6:339-348.
  • Agnesi F, Tye SJ, Bledsoe JM, Griessenauer CJ, Kimble CJ, Sieck GC, Bennet KE, Garris PA, Blaha CD, Lee, KH (2009) Wireless Instantaneous Neurotransmitter Concentration System-based amperometric detection of dopamine, adenosine, and glutamate for intraoperative neurochemical monitoring. J Neurosurg 111:701-711.
  • Etherington LV, Patterson GE, Meechan L, Boison D, Irving AJ, Dale N, Frenguelli BG (2009) Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus. Neuropharmacol 56:429-437.
  • Wall MJ, Wigmore G, Lopatar J, Frenguelli BG, Dale N (2008) The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition. Neuropharmacol 55:1251-1258.
  • Bekar L, Libionka W, Tian GF, Xu Q, Torres A, Wang X, Lovatt D, Williams E, Takano T, Schnermann J, Bakos R, Nedergaard M (2008) Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor. Nature Medicine 14:75-80.
  • Lin JH, Lou N, Kang N, Takano T, Hu F, Han X, Xu Q, Lovatt D, Torres A, Willecke K, Yang J, Kang J, Nedergaard M (2008) A central role of connexin 43 in hypoxic preconditioning. J Neurosci 28:681-695.
  • Gourine AV, Dale N, Llaudet E, Poputnikov D, Spyer KM, Gourine VN (2007) Release of ATP in the central nervous system during systemic inflammation: Real-time measurement in the hypothalamus of conscious rabbits. J Physiol 585, 305-326
  • Wall M, Atterbury A, Dale N (2007) Control of basal extracellular adenosine concentration in rat cerebellum. J Physiol 582:137-151.
  • Wall M, Dale N (2007) Auto-inhibition of parallel fibre-Purkinje cell synapses by activity dependent adenosine release. J Physiol 581:553-565.
  • Pearson T, Damian K, Lynas RE, Frenguelli BG (2006) Sustained elevation of extracellular adenosine and activation of A1 receptors underlie post-ischaemic inhibition of neuronal function in rat hippocampus in vitro. J Neurochem 97:1357:1368.
  • Dulla CG, Dobelis P, Pearson T, Frenguelli BG, Staley KJ, Masino SA (2005) Adenosine and ATP link PCO2 to cortical excitability via pH.  Neuron 48:1011-1023.
  • Pearson T, Frenguelli BG (2004) Adrenoceptor subtype-specific acceleration of the hypoxic depression of excitatory synaptic transmission in area CA1 of the rat hippocampus.  Eur J Neurosci 20:1555-1565.
  • Frenguelli BG, Llaudet E, Dale N (2003) High-resolution real-time recording with microelectrode biosensors reveals novel aspects of adenosine release during hypoxia in rat hippocampal slices. J Neurochem 86:1506-1515.
  • Llaudet E, Botting NP, Crayston JA, Dale N (2003) A three-enzyme microelectrode sensor for detecting purine release from central nervous system. Biosens Bioelectron 18:43-52.
  • Gourine AV, Llaudet E, Thomas T, Dale N, Spyer KM (2002) Adenosine release in nucleus tractus solitarii does not appear to mediate hypoxia-induced respiratory depression in rats. J Physiol 544:161-170.
  • Dale N, Gourine AV, Llaudet E, Bulmer D, Thomas T, Spyer KM (2002) Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo . J Physiol 544:149-160.
  • Begg M, Dale N, Llaudet E, Molleman A, Parsons ME (2002) Modulation of the release of endogenous adenosine by cannabinoids in the myenteric plexus-longitudinal muscle preparation of the guinea-pig ileum. Br J Pharmacol 137:1298-1304.
  • Pearson T, Nuritova F, Caldwell D, Dale, N, Frenguelli BG (2001) A depletable pool of adenosine in area CA1 of the rat hippocampus. J Neurosci 21:2298-2307.
  • Dale N, Pearson T, Frenguelli BG (2000) Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal slice. J Physiol 526:143-155.
  • Dale N (1998) Delayed production of adenosine underlies temporal modulation of swimming in frog embryo. J Physiol 511:265-272.
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