Adenosine and sleep

02 April 2012 at 00:00:00 by sarissa2

Another important breakthrough using Sarissa's biosensors. In a new paper in J Neurosci, Dr Phil Haydon's group have used sarissaprobe adenosine and inosine biosensors to demonstrate the important role of astrocytes in the diurnal control of adenosine release and the release of adenosine in response to sleep deprivation:

Schmitt LI, Sims RE, Dale N, Haydon PG. (2012) Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine. J Neurosci 32:4417-4425.

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