Sarissa Biomedical Ltd together with its partners, the Oxford Academic Health Science Network, Newcastle University's Stroke Research Group, Northumbria University and Coventry University's HDTI, is pleased to report that it has been awarded £150,000 Phase 1 grant from Innovate UK's Small Business Research Initiative (SBRI) Stratified medicine: connecting the UK infrastructure call for its 'Point of Care stroke IVD for Paramedic use' project ... Read More
The fMRI BOLD signal forms the basis of almost all modern functional brian imaging studies. The origins of this signal remain unclear. A superb new paper establishes a link between the rapid activity-depdendent release of ATP and the generation of fMRI BOLD responses in somatosensory cortex. This is a landmark paper that changes the field, and Sarissa's ATP biosensors helped the authors to develop the evidence to substantiate their findings. ... Read More
We are very pleased to be able to offer our customers a new purpose built potentiostat. This new device, designed for use with our microelectrode biosensors, offers a cost effective way to make simultaneous dual biosensor recordings. It features the ability to measure small (pA to nA) currents at low noise, and allows the use to see the current on each biosensor as well as the differential current between the channels -ideal for subtracting t ... Read More
Trotman M, Vermehran P, Gibson CL, Fern R (2014) The dichotomy of memantine treatment for ischemicstroke: dose-dependent protective and detrimental effects. J Cereb Blood Flow & Metab doi:10.1038/jcbfm.2014.188
This new paper examing the mechanisms of excitotoxic cell death relevant to stroke. The paper comes to the surpri ... Read More
Congratulations to the authors of recent papers that use a selection of our biosensors.
This paper features our ATP biosensors:
Lalo U, Palygin O, Rasooli-Nejad S, Andrew J, Haydon PG, Pankratov Y (2014) Exocytosis of ATP From Astrocytes Modulates Phasic and Tonic Inhibition in the Neocortex. PLoS Biol 12: e100174 ... Read More